Subacute toxicity of two polyoxyethylene-type nonionic surfactants on antioxidative defense system in the zebrafish Danio rerio

Authors

Qinghua Geng Dalian ocean university, Dalian 116023, China
Jianfeng Ding Dalian ocean university, Dalian 116023, China
Li Jiang Dalian ocean university, Dalian 116023, China
Yin Wu Dalian ocean university, Dalian 116023, China
Pengyun Bao Dalian ocean university, Dalian 116023, China

Keywords:

Subacute toxicity, Polyoxyethylene-type nonionic surfactants, Antioxidative defense system, Lipid peroxidation

Abstract

The main purpose of this study is to study the toxic effect of short-term nonionic surfactants dibenzyl phenol polyoxyethylene ether (BP) and fatty alcohol polyoxyethylene ether (AEO) exposure on the zebra fish Danio rerio. After treatment with different concentrations (0 mg/L, 0.25 mg/L, 0.5 mg/L, 1 mg/L, 2 mg/L) of BP and AEO for 30 days, the catalase (CAT) and superoxide dismutase (SOD) activities increased while the glutathione (GSH) content decreased in liver tissue of experimental zebrafish, and no significant different changes were observed in levels of malondialdehyde (MDA) and total antioxidant capacity (T-AOC). These results indicated the nonionic surfactants BP and AEO had potential toxic effects on zabrafish antioxidant defense system, and supported the view that a relationship exists between pollution and immunomodulation in aquatic organisms.